Product: Prilocaine and Intermediates
CAS NO.: 721-50-6
Molecular Formula: C13H20N2O
Molecular Weight: 220.31
Description: White crystal or crystalline powder
Chemical names, synonyms: astra1512, astra1515, Citanest, L 67, l67
Minimum purity: 99%
It is a kind of needle-like crystals with the melting point being 37-38 ℃ and the boiling point being 159-162 ℃ (0.133kPa), and refractive index (nD20) being 1.5299. The Melting point is 167-168 ℃. It is soluble in water and ethanol, slightly soluble in chloroform. It has sour taste and bitter taste and is odorless.
Topological Polar Surface Area 41.1 A^2
Monoisotopic Mass 220.158 g/mol
Exact Mass 220.158 g/mol
It is a kind of local anesthetic drug.It is suitable for epidural anesthesia, conduction anesthesia and infiltration anesthesia.
Prilocaine is a toluidine derivative and intermediate-acting amino amide with local anesthetic property. Prilocaine stabilizes the neuronal membrane by preferential binding to and inhibiting depolarization of the voltage-gated sodium channel. This results in a decrease in membrane permeability and subsequent inhibition of the ionic sodium influx required for the initiation and conduction of impulses.
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