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Tadalafil Intermediates

Product categories of Tadalafil Intermediates, we are specialized manufacturers from China, Tadalafil Intermediates, Tadalafil Intermediate Aphrodisiac Drug suppliers/factory, wholesale high-quality products of Tadalafil Intermediate Chloropretadalafil R & D and manufacturing, we have the perfect after-sales service and technical support. Look forward to your cooperation!
Tadanafil intermediate cas 171489-59-1 Chloropretadalafil
Chemical Name 1R 3R METHYL 1 2 3 4 TETRAHYDRO 2 CHLOROACETYL 1 3 4 METHYLENEDIOXYPHENYL 9H PYRIDO 3 4 B INDOLE 3 CARBOXYLATE Molecular Formula C22H19ClN2O5 Formula Weight 426 85 CAS No 171489 59 1 An intermediate in the production of Tadalafil...
China Tadalafil Intermediates of with CE
Tadalafil IMpurity intermediate cas 171752-68-4
Chemical Name 1R 3R 9H PYRIDO 3 4 B INDOLE 3 CARBOXYLIC ACID 1 2 3 4 TETRAHYDRO 1 3 4 METHYLENEDIOXYPH ENYL METHYL ESTER HYDROCHLORIDE Molecular Formula C20H19ClN2O4 Formula Weight 386 82886 CAS No 171752 68 4 Sildenafil at 50 mg or 100 mg...
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Tadalafil Intermediates are Intermediates of tadalafil.
Tadalafil is an oral drug that is used for treating impotence (the inability to attain or maintain a penile erection) and benign prostatic hyperplasia (BPH). It is in a class of drugs called phosphodiesterase-5 (PDE5) inhibitors that also includes sildenafil (Viagra) and vardenafil (Levitra). Erection of the penis is caused by the filling of the penis with blood. Filling occurs because the blood vessels that bring blood to the penis increase in size and deliver more blood to the penis, and, at the same time, the blood vessels that take blood away from the penis decrease in size and remove less blood from the penis. Sexual stimulation that leads to an erection causes the production and release of nitric oxide in the penis. The nitric oxide causes an enzyme, guanylate cyclase, to produce cyclic guanosine monophosphate (cGMP). It is cGMP that is primarily responsible for increasing and decreasing the size of blood vessels carrying blood to and from the penis, respectively, and causing an erection. When the cGMP is destroyed by another enzyme, phosphodiesterase-5, the blood vessels return to their normal size, blood leaves the penis, and the erection ends. Tadalafil prevents phosphodiesterase-5 from destroying cGMP so that cGMP stays around longer. The persistence of cGMP leads to a more prolonged engorgement of the penis with blood.
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