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Top for Eliquis Raw Material Apixaban Prilocaine base api and intermediate cas 721-50-6 supply to Mauritius Suppliers

Product: Prilocaine and Intermediates 

CAS NO.: 721-50-6

Standard: BP,CP,USP

Molecular Formula: C13H20N2O

Molecular Weight: 220.31

Description: White crystal or crystalline powder

Package: 25KG/drums

Chemical names, synonyms: astra1512, astra1515, Citanest, L 67, l67

Minimum purity: 99%

Prilocaine and Intermediates 721-50-6

It is a kind of needle-like crystals with the melting point being 37-38 ℃ and the boiling point being 159-162 ℃ (0.133kPa), and refractive index (nD20) being 1.5299.  The Melting point is 167-168 ℃. It is soluble in water and ethanol, slightly soluble in chloroform. It has sour taste and bitter taste and is odorless.

Topological Polar Surface Area 41.1 A^2

Monoisotopic Mass 220.158 g/mol

Exact Mass 220.158 g/mol

It is a kind of local anesthetic drug.It is suitable for epidural anesthesia, conduction anesthesia and infiltration anesthesia.

Prilocaine is a toluidine derivative and intermediate-acting amino amide with local anesthetic property. Prilocaine stabilizes the neuronal membrane by preferential binding to and inhibiting depolarization of the voltage-gated sodium channel. This results in a decrease in membrane permeability and subsequent inhibition of the ionic sodium influx required for the initiation and conduction of impulses.

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