Home > Products > Other APIs > Febuxostat CAS 160844-75-7 Brand Name Uloric

Febuxostat CAS 160844-75-7 Brand Name Uloric

    Unit Price: USD 125 - 300 / Bag/Bags
    Payment Type: L/C,T/T,D/P
    Incoterm: FOB,CFR,CIF
    Min. Order: 100 Bag/Bags
    Delivery Time: 7 Days
Basic Info

Model No.: CAS 160844-75-7

Function: Disinfectant and Preservatives, Drug Treatment of Mental Disorder, Regulating Water and Salt, Electrolyte and Acid-Base Balance of Medicine

Certification: FDA, Reach

Grade Standard: Medicine Grade

Type: Chemical Reagent, Auxiliaries And Other Medicinal Chemical

State: Solid

Volatile: Not Volatile

Purity: 99%

Shelf Life: 3 Years

NMR: Conform

Brand Name: Jianfeng

IR: Conform

Appearance: Off-White Crystalline Powder, Odorless

Water: 0.15%

Assay: 99.9%

Heavy Metals: Compiles

Additional Info

Packaging: Drum,Package

Productivity: 2000kg

Brand: JF

Transportation: Ocean,Land,Air

Place of Origin: China

Supply Ability: 2000kg

Certificate: ISO90011

HS Code: 29349990.99

Port: Qingdao,Shanghai,Guangdong

Product Description

Febuxostat, sold under the brand names Uloric among others, is a medication used long-term to treat gout due to high uric acid levels. It is generally only recommended in those who cannot take allopurinol. When initially started, medications such as NSAIDs are often recommended to prevent gout flares. It is taken by mouth. Common side effects include liver problems, nausea, joint pain, and a rash. Serious side effects include an increased risk of death as compared with allopurinol, Stevens-Johnson syndrome and anaphylaxis. Use is not recommended during pregnancy or breastfeeding It inhibits xanthine oxidase thus reducing production of uric acid in the body. Febuxostat was approved for medical use in the European Union in 2008 and in the United States in 2009. No generic version is avaliable as of 2019. In the United Kingdom a month of treatment costs the NHS about 24 pounds. In the United States the wholesale cost of a month's worth of medication is about 320 USD.

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Febuxostat is used to treat chronic gout and hyperuricemia. Febuxostat is typically only recommended in those who cannot tolerate allopurinol. National Institute for Health and Clinical Excellence Dainipon Sumitomo concluded that febuxostat is more effective than standard doses of allopurinol, but not more effective than higher doses of allopurinol. It is a non-purine-selective inhibitor of xanthine oxidase. It works by non-competitively blocking the molybdenum pterin center which is the active site on xanthine oxidase. Xanthine oxidase is needed to successively oxidize both hypoxanthine and xanthine to uric acid. Hence, febuxostat inhibits xanthine oxidase, therefore reducing production of uric acid. Febuxostat inhibits both oxidized as well as reduced form of xanthine oxidase because of which febuxostat cannot be easily displaced from the molybdenum pterin site.

Looking for ideal High Uric Acid Levels Febuxostat Manufacturer & supplier ? We have a wide selection at great prices to help you get creative. All the Brand Name Uloric are quality guaranteed. We are China Origin Factory of Chronic Gout Treating Medicine. If you have any question, please feel free to contact us.

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