http://www.pharmachemm.com
Home > Products > Other APIs > Raltegravir cas 518048-05-0 Raltegravir free base

Raltegravir cas 518048-05-0 Raltegravir free base

Basic Info

Function: Antibiotic and Antimicrobial Agents

Grade Standard: Medicine Grade

Type: Chemical Reagent

State: Solid

Volatile: Not Volatile

Product Description

Raltegravir (RAL), sold under the brand name Isentress, is an antiretroviral medication used, together with other medication, to treat HIV/AIDS. It may also be used, as part of post exposure prophylaxis, to prevent HIV infection following potential exposure. It is taken by mouth.The product belongs to Antiviral class.
Common side effects include trouble sleeping, feeling tired, nausea, high blood sugar, and headaches. Severe side effects may include allergic reactions including Stevens-Johnson syndrome, muscle breakdown, and liver problems. It is unclear if use during pregnancy or breastfeeding is safe. Raltegravir is an HIV integrase strand transfer inhibitor which blocks the functioning of HIV integrase which is needed for viral replication.
Raltegravir was approved for medical use in the United States in 2007. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. The wholesale cost in the developing world is about 50 USD per month. In the United Kingdom it costs the NHS about 472.00 pounds per month. Lamivudine/raltegravir, a combination with lamivudine, is also available.
Merck's Raltegravir is the first HIV integrase strand transfer inhibitor (referred to as an integrase inhibitor). It is also known as MK-0518, which can treat human immunodeficiency virus (HIV)-1 infection combining with other antiretroviral (ARV) drugs. It slows HIV-1 infection by inhibiting the necessary HIV integrase for viral replication. When raltegravir combines with other anti-HIV drugs, it can reduce the amount of HIV in the blood, while it can increase the number of so-called CD4+ T cells that belong to white blood cells. It helps against other infections. The interaction between raltegravir and ritonavir, efavirenz, tipranavir and tenofovir indicates that there is no drug cross-resistance, and there is a synergistic effect with a variety of drugs. The most common adverse reactions are diarrhea, nausea, headache. In addition, blood tests show that the muscle enzymes abnormally increased in some of patients who taked this drug. Key words of the product are
Raltegravir (Free Base) Api Purity 99%, Raltegravir Ral Isentress and Antiretroviral Medication Drug

Chemical Name: Raltegravir
Molecular Formula: C20H21FN6O5
Formula Weight: 444.42

CAS No.: 518048-05-0


Looking for ideal Raltegravir Api Purity 99% Manufacturer & supplier ? We have a wide selection at great prices to help you get creative. All the Raltegravir Ral Isentress are quality guaranteed. We are China Origin Factory of Antiretroviral Medication Drug. If you have any question, please feel free to contact us.

Product Categories : Other APIs

Email to this supplier
  • *Subject:
  • *Messages:
    Your message must be between 20-8000 characters
Communicate with Supplier?Supplier
Mr. Vid Mr. Mr. Vid
What can I do for you?
Contact Supplier