Chemical Name: ISOPRINOSINE
Molecular Formula: C52H78N10O17
Formula Weight: 1115.23
CAS No.: 36703-88-5
Isoprinosine is a medicine that contains an active substance called inosine acedoben dimepranol. It belongs to a group of medicines called immunomodulators with antiviral effect. It is used in the treatment of herpes simplex infections, genital warts and subacute sclerosing panencephalitis (brain damage accompanied by mental deterioration and convulsions).
Inosine pranobex (BAN; also known as inosine acedoben dimepranol (INN) or methisoprinol) an antiviral drug that is a combination of inosine and dimepranol acedoben (a salt of acetamidobenzoic acid and dimethylaminoisopropanol) in a ratio of 1 to 3. Inosine pranobex has no effect on viral particles itself. Instead, it acts as an immunostimulant, an analog of thymus hormones. It is most commonly used to treat the rare measles complication subacute sclerosing panencephalitis in conjunction with intrathecal interferon therapy.
The immunopharmacologic effects of Isoprinosine (INPX) have been associated with clinical benefit to the patient in a number of conditions characterized by immunodeficiency of diverse etiology. Immunodepressed homosexuals at risk of developing acquired immunodeficiency syndrome (AIDS) treated with placebo or INPX experienced an increase in the function and number of immunocompetent cells associated with clinical improvement. A multicenter trial designed to confirm these results has demonstrated that INPX produced an increase in natural killer (NK)-cell activity, total T cells, and T-helper cells, with certain effects persisting for months after completion of the 28-day treatment period.
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