Chemical Name: TIANEPTINE
Molecular Formula: C21H25ClN2O4S
Formula Weight: 436.95
CAS No.: 66981-73-5
Chemical Name: tianeptine sulfate
Molecular Formula: 2(C21H25ClN2O4S).H2SO4.2(H2O)
CAS No.: 1224690-84-9
Tianeptine has antidepressant and anxiolytic effects with a relative lack of sedative, anticholinergic, and Cardiovascular side effects. It has been found to act as an atypical agonist of the μ-opioid receptor with clinically negligible effects on the δ- and κ-opioid receptors. μ-Opioid receptor agonists typically induce euphoria, and in accordance, tianeptine does so at high doses well above the normal therapeutic range.
Tianeptine is an antidepressant agent with a novel neurochemical profile. It increases serotonin (5-hydroxytryptamine; 5-HT) uptake in the brain (in contrast with most antidepressant agents) and reduces stress-induced atrophy of neuronal dendrites. Like the selective serotonin reuptake inhibitors (SSRIs) and in contrast with most tricyclic antidepressant agents, tianeptine does not appear to be associated with adverse cognitive, psychomotor, sleep, cardiovascular or bodyweight effects and has a low propensity for abuse. Tianeptine has a comparatively favourable pharmacokinetic profile. It is not subject to first-pass hepatic metabolism, has high bioavailability and limited distribution, and is rapidly eliminated. While this offers advantages for tianeptine over the tricyclic antidepressant agents in terms of dose titration, treatment changes and potential drug interactions, its rapid elimination makes adherence to dosage schedules more important.
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Product Categories : Antipsychotic/Psychiatric/Mental