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20127-57-1 Mesilate cas 152459-95-5

    Incoterm: FOB,CIF
    Min. Order: 1 Bag/Bags
    Delivery Time: 1 Days
Basic Info

Model No.: jianfeng

Function: Antineoplastic, Respiratory System Agents, Anesthetic and Adjuvant

Grade Standard: Medicine Grade

Type: Chemical Reagent

State: Solid

Volatile: Not Volatile

Assay: 99%

Certification: FDA

Additional Info

Packaging: bag

Productivity: 2000kg

Brand: Jianfeng

Transportation: Land

Place of Origin: China

Supply Ability: 2045kg

Certificate: ISO

HS Code: 29349990.06

Port: Shanghai

Product Description

Imatinib is a small molecule kinase inhibitor used to treat certain types of cancer. It is currently marketed by Novartis as Gleevec (USA) or Glivec (Europe/Australia) as its mesylate salt, imatinib mesilate (INN). It is occasionally referred to as CGP57148B or STI571 (especially in older publications).Product Name: Imatinib Mesilate

CAS NO: 220127-57-1

Standard: Enterprise Standard

Molecular Formula: C30H35N7O4S

Molecular Weight : 589.71

Description: White crystal or crystalline powder

Package :25KG/drums

Chemical names, synonyms:


4-[(4-methyl-1-piperazinyl)methyl]-n-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-benzamide monomethanesulfonate, STI-571, IMATINIB BASE(IMA-3), Imatinib (STI-571) Mesylate



Minimum purity: 99%

Imatinib Mesilate 220127-57-1

Description

White to off-white Crystalline Powder

Identification By IR

IR spectrum of the sample should concordant to the standard spectrum.

Solubility

Soluble in Water

LOD

NMT 0.5% w/w

Related substance

by HPLC

Single Max. Imp : NMT 0.1 %

Total Max Imp : NMT 1.0 %

Assay (By HPLC)

NMT 98.0% And NLT 102 %

ROI

NMT 0.5%

Heavy metals

NMT 0.5%

Thermo gram

220-227ºC

Imatinib Mesylate is a targeted therapy. Imatinib Mesylate is classified as a signal transduction inhibitor - protein-tyrosine kinase inhibitor.

A methanesulfonate (mesylate) salt that is the monomesylate salt of imatinib. Used for treatment of chronic myelogenous leukemia and gastrointestinal stromal tumours.

Imatinib mesylate (also called Gleevec) is a small-molecule inhibitor of the fusion protein Bcr-Abl, the causal agent in chronic myelogenous leukemia.

As an inhibitor of PDGFR, imatinib mesylate appears to have utility in the treatment of a variety of dermatological diseases. Imatinib has been reported to be an effective treatment for FIP1L1-PDGFRalpha+ mast cell disease, hypereosinophilic syndrome, and dermatofibrosarcoma protuberans.



Looking for ideal Imatinib Mesilate API IMatinib-D4 Manufacturer & supplier ? We have a wide selection at great prices to help you get creative. All the Imatinib Base Gleevec Pills are quality guaranteed. We are China Origin Factory of Imatinib Mesilate Intermediate. If you have any question, please feel free to contact us.

Product Categories : Anticancer/Antitumor/Antineoplastic

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