CAS NO.: 6108-05-0
Molecular Formula: C14H25ClN2O2
Molecular Weight: 288.81
Description: White crystal or crystalline powder
Chemical names, synonyms:
Minimum purity: 99%
Cas 6108-05-0 is also the most important class-1b antiarrhythmic drug; it is used intravenously for the treatment of ventricular arrhythmias (for acute myocardial infarction, digoxin poisoning, cardioversion, or cardiac catheterization) if amiodarone is not available or contraindicated. Cas 6108-05-0 should be given for this indication after defibrillation, CPR, and vasopressors have been initiated. A routine preventative dose is no longer recommended after a myocardial infarction as the overall benefit is not convincing.
6108-05-0 Hydrochloride is the hydrochloride salt from of 6108-05-0, an aminoethylamide and a prototypical member of the amide class anesthetics. 6108-05-0 interacts with voltage-gated Na+ channels in the nerve cell membrane and blocks the transient increase in permeability of excitable membranes to Na+. This prevents the generation and conduction of nerve impulses and produces a reversible loss of sensation. 6108-05-0 hydrochloride also exhibits class IB antiarrhythmic effects. The agent decreases the flow of sodium ions into myocardial tissue, especially on the Purkinje network, during phase 0 of the action potential, thereby decreasing depolarization, automaticity and excitability
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