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Lapatinib API Lapatinib Intermedicate cas 231277-92-2

Product Description

Product Name: Lapatinib

CAS NO.: 231277-92-2

Molecular Formula: C29H26ClFN4O4S

Molecular Weight: 581.0575432

Description: White crystal or crystalline powder

Package: 25KG/drums

Chemical names, synonyms: Lapatinib(TINIBS), Lapatinib free base, GSK572016, GW 57201, Lapatinib(ditosylate salt), Lapatinib ditosylate

Minimum purity: 99%


Lapatinib 231277-92-2


Lapatinib is a synthetic, orally-active quinazoline with potential antineoplastic activity. Lapatinib reversibly blocks phosphorylation of the epidermal growth factor receptor (EGFR), ErbB2, and the Erk-1 and-2 and AKT kinases; it also inhibits cyclin D protein levels in human tumor cell lines and xenografts. EGFR and ErbB2 have been implicated in the growth of various tumor types. Check for active clinical trials or closed clinical trials using this agent.
Lapatinib is an anti-cancer drug developed by GlaxoSmithKline (GSK) as a treatment for solid tumours such as breast and lung cancer. It was approved by the FDA on March 13, 2007, for use in patients with advanced metastatic breast cancer in conjunction with the chemotherapy drug Capecitabine. Lapatinib is human epidermal growth factor receptor type 2 (HER2/ERBB2) and epidermal growth factor receptor (HER1/EGFR/ERBB1) tyrosine kinases inhibitor. It binds to the intracellular phosphorylation domain to prevent receptor autophosphorylation upon ligand binding.


Looking for ideal Lapatinib Powder Pruity 99% Manufacturer & supplier ? We have a wide selection at great prices to help you get creative. All the Lapatinib Raw Materical are quality guaranteed. We are China Origin Factory of Lapatinib Ditosylate Salt. If you have any question, please feel free to contact us.

Product Categories : Anticancer/Antitumor/Antineoplastic

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